Roz Garber evaded the KGB to bring hope to refuseniks in the USSR. She became involved in the issue of Soviet Jewry with her husband, and the two were chosen for a secret mission run by the Jewish Agency in 1975: to travel to the Soviet Union and give refuseniks educational materials and information about Israel. During the three-week trip, they met with refuseniks, but had to be careful not to give themselves away to KGB agents planted in synagogues. The experience underscored to them the risks refuseniks regularly took in practicing Judaism. They were finally intercepted by the KGB, who followed them throughout the rest of their trip and prevented them from contacting more refuseniks. Upon their return from the Soviet Union, Garber and her husband used speaking tours to educate the American Jewish community about conditions for Jews in the Soviet Union. After the fall of the Soviet Union, Garber served in leadership roles for several important Jewish organizations, including Hadassah, and was the CEO and president of a highly successful travel agency, Garber Travel Services, Inc.

Roz Garber was honored at the 2000 Women Who Dared event in Boston.